Find a Physician

Return to Pediatric Tumor and Bone Disease Center Overview

More on Pediatric Tumor and Bone Disease Center

Clinical Services

Return to Pediatric Tumor and Bone Disease Center Overview

More on Pediatric Tumor and Bone Disease Center

Health Information

Return to Pediatric Tumor and Bone Disease Center Overview

More on Pediatric Tumor and Bone Disease Center

Research and Clinical Trials

Return to Pediatric Tumor and Bone Disease Center Overview

More on Pediatric Tumor and Bone Disease Center

For Patients, Families & Visitors

Return to Pediatric Tumor and Bone Disease Center Overview

More on Pediatric Tumor and Bone Disease Center

Professionals

Return to Pediatric Tumor and Bone Disease Center Overview

More on Pediatric Tumor and Bone Disease Center

Hospital News

Return to Pediatric Tumor and Bone Disease Center Overview

More on Pediatric Tumor and Bone Disease Center

Orthopaedic Surgery

Pediatric Tumor and Bone Disease Center

Dr. Francis Y. Lee joined the Division of Orthopaedic Surgery in 1999 after completing a Musculoskeletal Tumor Fellowship at the Massachusetts General Hospital and Boston Children's Hospital, and a Pediatric Orthopedic Surgery Fellowship at the Hospital for Sick Children in Toronto.

Dr. Lee is currently an Assistant Professor of Orthopedic Surgery at Columbia University College of Physician and Surgeons, specializing in pediatric orthopedic surgery, including spine deformity and complex developmental orthopedic disorders, musculoskeletal tumors and bone disease. He serves as the Chief of the Tumor and Bone Disease service and Director of the Center for Orthopedic Research. He is conducting both basic and clinical studies on musculoskeletal disorders. He is a recipient of the American Academy of Orthopaedic Surgeons/Orthopaedic Research Education and Foundation Clinician Scientist Traveling Fellowship Award (2004-2005).

Dr. Lee was recently appointed Vice Chairman of Research in the Department of Orthpedic Surgery, and is one of a handful of orthopaedic surgeons with an NIH-R01 research grant.

Current Research Programs

As an orthopaedic surgeon who has been involved in the care of patients with bone and soft tissue sarcomas, Dr. Lee naturally thinks about a new paradigm for more efficacious treatments. There are two fundamental issues in the musculoskeletal oncology practice. The first issue is reconstruction of massive skeletal or muscular defect after complete surgical removal of tumor. The second issue is life saving with respect to tumor recurrence, and spread of tumor to lungs and death. These two multidisciplinary research programs are innovative, human disease-oriented translational research projects which meet the goals of the new NIH Roadmap.

Basic Research
  • Enhancement of Prosthesis Longevity: A new perspective
  • Summary of Current Molecular Tribology / Mechanobiology Program (Excerpt from NIH R01EB006834-01A1: Priority score 137; Percentile score: 1.7%):
  • Sarcoma Research Program
    - A Novel Treatment for Sarcomas using small interfering RNA and mesenchymal stem cells
    - Discovery of Oncogenes Responsible for Sarcomas
Clinical Research
  • Outcome Research on Bone and Soft Tissue Tumors
  • Pediatric Orthopaedic Trauma and Disorders

  • Bookmark
  • Print


Top of page