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Francis Y. Lee, MD, PhD, Among Columbia Researchers to Receive U.S. Department of Defense Award of $3.2 Million for Research to Help Wounded Military Personnel

Francis Y. Lee, MD, PhD, Chief of Tumor and Bone Disease, Morgan Stanley Children's Hospital, and Associate Professor of Orthopaedic Surgery and Vice Chair for Research, Columbia University Medical Center; Jeremy Mao, DDS, PhD, Columbia University College of Dental Medicine; Edward V. Zegarelli, Professor of Dental Medicine, Columbia University College of Dental Medicine; and Andreas Hielscher, PhD, Associate Professor of Biomedical Engineering, Columbia University, have received a four-year grant of $3.2 million from the Department of Defense for their research project, "Ready-to-Use Tissue Constructs for Military Trauma Bone and Cartilage Defects." This large grant exemplifies successful multidisciplinary collaboration among the Columbia University Medical Center, Columbia University College of Dental Medicine, and Columbia University Morningside campuses.

As a collective effort, Dr. Lee, orthopaedic clinician-scientist; Dr. Mao, tissue engineering expert; and Dr. Hielscher, 3D optical tomography (OT) imaging authority; will examine the potential of ready-to-use tissue constructs with optimal growth factors for regeneration of massive cartilage/bone defects resulting from military combat related injuries. The researchers also have ongoing National Institutes of Health-funded projects on bone inflammation, tissue engineering and optical imaging, respectively.

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